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Drug Half-Life Calculator: Medication Elimination

Calculate how long a substance remains in the body.

What is Biological Half-Life?

The half-life of a drug is the time it takes for the concentration of the substance in the body to be reduced by exactly one half (50%). It helps determine dosing schedules and withdrawal times.

The Formula

  1. The decay is exponential.
  2. Formula: Remaining Amount = Initial Dose × (0.5)^(Time Elapsed / Half-Life).
  3. Generally, it takes about 5.5 half-lives for a drug to be considered effectively eliminated from the system.

Pharmacology FAQs

Does half-life change with dose?

For most drugs (first-order kinetics), the half-life remains constant regardless of the dose. For some (like alcohol), the rate of elimination is constant rather than proportional.